During boot in QEMU on a MacBook Air M1 - not sure exactly which operation caused it:

0.337 [#0 SyncTask(3:3)]: SyncTask is running
0.345 [#0 init_stage2(1:1)]: BIOSSysFSDirectory: SMBIOS 32bit Entry point @ P00000000000f59b0
0.345 [#0 init_stage2(1:1)]: BIOSSysFSDirectory: Data table @ P00000000000f59d0
0.353 [#0 init_stage2(1:1)]: VirtIOConsole: Found @ PCI [0000:00:03:00]
0.353 [#0 init_stage2(1:1)]: Trying to unregister unused handler (?)
0.369 [#0 init_stage2(1:1)]: VirtIO::Console: cols: 0, rows: 0, max nr ports 2
0.387 [#0 init_stage2(1:1)]: VirtIORNG: Found @ PCI [0000:00:04:00]
[IO WorkQueue(2:2)]: ASSERTION FAILED: handler
[IO WorkQueue(2:2)]: ./Kernel/Arch/x86/common/Interrupts.cpp:491 in void Kernel::handle_interrupt(Kernel::TrapFrame*)
[IO WorkQueue(2:2)]: KERNEL PANIC! :^(
[IO WorkQueue(2:2)]: Aborted
[IO WorkQueue(2:2)]: at ./Kernel/Arch/x86/common/CPU.cpp:35 in void abort()
[IO WorkQueue(2:2)]: Kernel + 0x00cbf801  Kernel::__panic(char const*, unsigned int, char const*) +0xf1
[IO WorkQueue(2:2)]: Kernel + 0x0106b989  abort.localalias +0x245
[IO WorkQueue(2:2)]: Kernel + 0x0106b744  abort.localalias +0x0
[IO WorkQueue(2:2)]: Kernel + 0x0107d6ff  handle_interrupt +0x3cf
[IO WorkQueue(2:2)]: Kernel + 0x0106884b  interrupt_common_asm_entry +0x2b
[IO WorkQueue(2:2)]: Kernel + 0x010473b3  void Kernel::Process::kernel_process_trampoline<Kernel::WorkQueue::WorkQueue(AK::StringView)::{lambda()#1}>(void*) +0x5e3
[IO WorkQueue(2:2)]: Kernel + 0x0108acc0  exit_kernel_thread +0x0 ```

On a second boot this did not happen.